Top Flea & Tick Solutions for 2025: Review of Seresto Collars & Frontline Plus

Best flea and tick products

If you’re a pet parent, you know the dreaded flea-and-tick season can feel like a never-ending battle. These tiny pests can cause itching, skin infections, and even transmit diseases.
The good news? Prevention has never been easier with modern flea and tick products.

In this guide, we’re breaking down four popular, vet-recommended products:

  1. Seresto Collar for Dogs
  2. Frontline Plus for Cats
  3. Seresto Collar for Cats
  4. Frontline Plus for Dogs

We’ll go over how each works, what pet parents love (and don’t love), and tips to pick the right one.

1. Seresto Collar for Dogs:

Where to buy:

Seresto Collar For Large Dogs (Over 18 Lbs) 27.5 Inch (70 Cm) 2 Collar

What it is:
Seresto is a long-lasting flea and tick prevention collar that protects dogs for up to 8 months. It releases low doses of active ingredients that kill and repel fleas and ticks.Z

Why dog parents love it:

  • Set it and forget it: One collar lasts months.
  • Water-resistant: Rain and occasional baths don’t affect it.
  • No grease or smell: Unlike topical products, it’s mess-free.

Things to consider:

  • Dogs may need a day or two to get used to it.
  • Heavy swimmers may need to replace it earlier.

Best for: Busy owners who prefer low-maintenance, continuous protection.

2. Seresto Collar for Cats

Where to buy:

Seresto Collar For Cats 3 Collar

What it is:
This odorless flea and tick collar works up to 8 months and is designed just for cats. It also has a breakaway mechanism for safety.

Why cat parents love it:

  • Long-term: One collar gives season-long protection.
  • Odorless: Great for sensitive cats.
  • Safe: Breakaway feature prevents choking.

Things to consider:

  • Some cats dislike wearing collars.
  • Must ensure it’s fitted correctly.

Best for: Cat owners who want no-fuss, long-term prevention.

3. Frontline Plus for Cats

Where to buy:

Frontline Plus For Cats 3 Doses

What it is:
Frontline Plus for Cats is a monthly spot-on treatment. It’s applied to the back of your cat’s neck, where it quickly spreads over the skin to kill fleas, flea eggs, and ticks.

Why cat parents love it:

  • Fast action: Starts killing fleas in 12 hours.
  • Breaks the cycle: Eliminates eggs and larvae.
  • Easy to use: A quick monthly application.

Things to consider:

  • Cats don’t always like the liquid applied.
  • Needs regular monthly reapplication.

Best for: Cats that hate wearing collars but need protection.

4. Frontline Plus for Dogs

Where to buy:

Frontline Plus For Extra Large Dogs Above 88lbs (Red) 3 Doses

What it is:
Frontline Plus for Dogs is a monthly topical solution applied to your dog’s back. It targets fleas, flea eggs, ticks, and lice, and is water-resistant after 24 hours.

Why dog parents love it:

  • Kills fleas fast: Works within 12 hours.
  • Dual action: Kills adult fleas and stops eggs from hatching.
  • Easy to apply: Just once a month.

Things to consider:

  • Requires monthly application.
  • Avoid bathing for 24 hours after applying.

Best for: Owners who prefer a monthly routine and don’t want their dog to wear a collar.

Collars vs. Topical Treatments – Which One Should You Pick?

Here’s a quick decision guide:

  • Forgetful owners? Go for Seresto collars (8-month protection).
  • Cats who dislike collars? Use Frontline Plus for Cats.
  • Dogs with sensitive necks or heavy swimmers? Frontline Plus for Dogs might suit better.
  • Outdoor pets needing constant coverage? Seresto collars are ideal.

Flea & Tick Prevention Tips

  • Check your pets weekly: Even with protection, a quick coat check is smart.
  • Clean your home: Vacuum often to remove hidden flea eggs.
  • Treat every pet in the house: Fleas can hop between them.
  • Ask your vet: When in doubt, get professional advice.

FAQ: Flea & Tick Products

1. Are these products safe for young pets?

  • Seresto: Safe for dogs over 7 weeks and cats over 10 weeks.
  • Frontline Plus: Safe for puppies and kittens 8+ weeks.

2. Can I mix a collar and a topical treatment?
No, unless your vet specifically recommends it.

3. How fast do they work?

  • Seresto: Kills fleas within 24 hours.
  • Frontline Plus: Starts killing fleas within 12 hours.

4. Prescription needed?
No prescription required for these products on PetCareSupplies.

Disclaimer: We may earn commission from links—but every product is paw-tested by our team. Consult your vet for personalized care plans.